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Enhanced bone marrow suppression by cyclophosphamide and other cytotoxic agents has been reported among patients with neoplastic diseaseexcept leukemiain the presence of ZyloprimHoweverin a well-controlled study of patients with lymphoma on combination therapyZyloprim did not increase the marrow toxicity of patients treated with cyclophosphamidedoxorubicinbleomycinprocarbazineand/or mechlorethamine.

Enhanced bone marrow suppression by cyclophosphamide and other cytotoxic agents has been reported among patients with neoplastic diseaseexcept leukemiain the presence of ZyloprimHoweverin a well-controlled study of patients with lymphoma on combination therapyZyloprim did not increase the marrow toxicity of patients treated with cyclophosphamidedoxorubicinbleomycinprocarbazineand/or mechlorethamine.

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